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          精制甲型肝炎滅活疫苗(YN5株)狨猴試驗安全性和免疫原性

            【摘要】 目的檢測精制甲型肝炎滅活疫苗的安全性和免疫原性。方法甲型肝炎病毒YN-5株經Veto細
          胞培養制成精制甲型肝炎滅活疫苗。采用普通狨猴(common腳Ⅱn0se【)進行疫苗的安全性、免疫原性和保護力試驗。
          結果實驗疫苗組和對照疫苗組狨猴均有特異抗體產生,對甲型肝炎病毒強毒株的攻擊亦有保護作用。結論該
          疫苗(YN.5株)有良好的安全性和免疫原性。
            【關鍵詞】普通狨猴;甲型肝炎滅活疫苗;安全性;免疫原性

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