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          傷寒Vi多糖柱層析純化工藝的優化
          傷寒Vi多糖柱層析純化工藝的優化

          摘要目的:優化傷寒Vi 多糖柱層析純化工藝,以替代傳統苯酚抽提、乙醇分級沉淀法。方法:采用DEAE 離子交換層析柱,分別在緩沖液(20 mmol/L Tris-Cl)pH 值為6. 0、7. 0 和8. 0 的條件下純化1 批傷寒Vi 多糖粗糖,并與傳統苯酚抽提、乙醇分級沉淀法進行比較。按《中國藥…[詳情]

          精制甲型肝炎滅活疫苗(YN5株)狨猴試驗安全性和免疫原性
          精制甲型肝炎滅活疫苗(YN5株)狨猴試驗安全性和免疫原性

          【摘要】 目的檢測精制甲型肝炎滅活疫苗的安全性和免疫原性。方法甲型肝炎病毒YN-5株經Veto細胞培養制成精制甲型肝炎滅活疫苗。采用普通狨猴(common腳Ⅱn0se【)進行疫苗的安全性、免疫原性和保護力試驗。結果實驗疫苗組和對照疫苗組狨猴均有特異抗體產生,對甲型肝炎病毒…[詳情]

          凤凰彩票

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